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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLAU
All Species:
20.3
Human Site:
T335
Identified Species:
49.63
UniProt:
P00749
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P00749
NP_001138503.1
431
48507
T335
Y
P
E
Q
L
K
M
T
V
V
K
L
I
S
H
Chimpanzee
Pan troglodytes
XP_528120
687
76517
A591
Y
S
E
R
L
K
E
A
H
V
R
L
Y
P
S
Rhesus Macaque
Macaca mulatta
XP_001099358
430
48241
T334
Y
P
E
R
L
K
M
T
V
V
K
L
V
S
H
Dog
Lupus familis
XP_536394
543
59426
T447
Y
P
E
Q
L
K
M
T
V
V
K
L
V
S
H
Cat
Felis silvestris
Mouse
Mus musculus
P06869
433
48249
S337
Y
P
K
N
L
K
M
S
V
V
K
L
V
S
H
Rat
Rattus norvegicus
P29598
432
47939
S336
Y
P
K
D
L
K
M
S
V
V
K
I
I
S
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510562
432
48862
S329
Y
S
N
H
L
K
T
S
R
V
N
L
I
S
H
Chicken
Gallus gallus
P15120
434
49381
A332
Y
A
Q
R
L
M
S
A
T
V
N
L
I
S
Q
Frog
Xenopus laevis
NP_001083592
553
62071
G457
Y
S
E
Q
L
K
E
G
H
V
R
L
Y
P
D
Zebra Danio
Brachydanio rerio
XP_001346717
292
32083
E197
F
Y
S
Q
Y
L
K
E
A
Q
V
K
I
L
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
30.1
93
61.8
N.A.
69
71.3
N.A.
55.5
46.5
35.4
31
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
41
96.9
69.2
N.A.
81.9
83
N.A.
68.7
62.6
45.3
43.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
40
86.6
93.3
N.A.
73.3
73.3
N.A.
53.3
40
46.6
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
53.3
100
100
N.A.
93.3
93.3
N.A.
60
53.3
53.3
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
0
0
20
10
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
10
% D
% Glu:
0
0
50
0
0
0
20
10
0
0
0
0
0
0
0
% E
% Phe:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% G
% His:
0
0
0
10
0
0
0
0
20
0
0
0
0
0
60
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
10
50
0
0
% I
% Lys:
0
0
20
0
0
80
10
0
0
0
50
10
0
0
0
% K
% Leu:
0
0
0
0
90
10
0
0
0
0
0
80
0
10
0
% L
% Met:
0
0
0
0
0
10
50
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
10
0
0
0
0
0
0
20
0
0
0
0
% N
% Pro:
0
50
0
0
0
0
0
0
0
0
0
0
0
20
0
% P
% Gln:
0
0
10
40
0
0
0
0
0
10
0
0
0
0
10
% Q
% Arg:
0
0
0
30
0
0
0
0
10
0
20
0
0
0
0
% R
% Ser:
0
30
10
0
0
0
10
30
0
0
0
0
0
70
20
% S
% Thr:
0
0
0
0
0
0
10
30
10
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
50
90
10
0
30
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
90
10
0
0
10
0
0
0
0
0
0
0
20
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _